Openings
Escape is seeking an enthusiastic scientist with experience and a focus in human embryonic
stem cell biology and directed differentiation to join our ESC Translational Program. This
person will help execute genetic engineering of an immune tolerance gene into human embryonic
stem cells, and perform in vitro and in vivo studies to evaluate survival of modified hESCs
and their derivatives.
Responsibilities
- Culture hESCs and direct differentiation to one or more cell fates (epidermal stem cells, fibroblasts, islet cells, HSCs, and MSCs)
- Perform flow cytometry, immunocytochemistry, and genetic engineering experiments
- Plan, coordinate and execute in vitro immunological assays
- Data analysis and training of researchers to assist in the studies
- Write and review manuscripts for publication
- Write and review grant applications
Qualifications
- The ideal candidate will have a Ph.D. in Stem Cell Biology or Immunology
- Experience with hESC culture, genetic engineering, and directed differentiation. Experience with human MSCs, immune tolerance, and stem cell transplantation models is desirable
- Excellent technical skills in most, if not all, of the following areas is required: molecular biology, flow cytometry, cell culture, and animal surgery
- The candidate must have completed his or her graduate degree at a top academic institution or with a recognized stem cell or immunology PI
- The candidate must have several high impact peer-reviewed publications
- Self motivated and ability to work independently, as well as contribute actively to an integrated team
- Excellent oral and written communications essential
