OsteoStem
OsteoStem is a bone repair product designed to improve the structure and function of injured or degenerating bone.
Escape will generate OsteoStem using a unique manufacturing process whereby ImmuStem or MesoStem cells are treated
with its proprietary osteogenic differentiation factor, OsteoFuse. When injected into the target bone site, OsteoStem
is believed to remodel and lay down collagen and other extracellular matrix components normally produced within bone.
In preliminary studies, Escape has shown that OsteoStem displays a dramatically reduced immunogenicity profile in
allorecognition studies. Escape's universal bone repair product allows for the creation of an off-the-shelf extracellular
matrix-producing osteogenic cell that can be transplanted into patients of any HLA type, without the need for lifelong
immunosuppression. Escape also believes that direct injection of OsteoFuse can dramatically enhance osteogenic
differentiation of a patient's own mesenchymal stem cells that have already been mobilized to the site of bone injury.
OsteoStem and OsteoFuse to revolutionize the treatment of common bone disorders such as acute fractures and osteoporosis,
amongst others.